Neural Prolotherapy

Dr. John Lyftogt, from New Zealand, struggled for years to help find some relief for his chronic pain patients.  He developed a treatment that he termed Neural Prolotherapy while working on relieving Achilles tendonopathy.  Neural Prolotherapy is an injection therapy with 5% dextrose (sugar) that focuses on treating the nerves in the skin that have become injured and entrapped due to inflammation.   Although the nerves are superficial, the pain they create is often felt in the deeper tissues.  The injection of low-dose dextrose changes the pain signaling and stops neurogenic inflammation (what your doctor may have called neuropathic pain).  The dextrose solution also has a regenerative effect on the entrapped nerves helping them to heal and preventing recurrence.

How does Neural Prolotherapy treatment work?

5% Dextrose is injected beneath the skin surface with a tiny needle over commonly constricted regions of nerves.  The working hypothesis considers that low dose 5% dextrose targets glucose sensing pain nerves called nociceptors found immediately under the skin.  Changing the receptors in the nerve allow for modulation of signals to deeper structures like tendons, ligaments and joints (Hilton’s law). Other substances also can alters these receptors such as procaine, magnesium and salt which may explain why Epsom salt bath soaks are so popular.

What is the treatment like?
Dr. Berghamer will track the pain by feeling for inflamed nerves in the skin. These nerves aren’t usually palpable but when they are inflamed and constricted they feel like small taut hoses that can be exquisitely painful to touch. Once the nerves have been tracked they are injected along their lengths with 5% dextrose.

To read more about Neural Prolotherapy, click here.

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Dr. Jonathon Friz Berghamer